Cardiovascular Health Research Unit

Colleen Sitlani, PhD

Research Scientist


AB, Applied Mathematics, Harvard University, 2000
MS, Biostatistics, University of Washington, 2008
PhD, Biostatistics, University of Washington, 2011


Longitudinal and correlated data analysis
Epidemiologic methods
Genetic and pharmacogenetic epidemiology
Causal inference
Classification and prediction


Outstanding Teaching Assistant, UW School of Public Health, 2006
Graduate Student Travel Award, ASA Section on Statistics in Epidemiology, 2009
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fellow, 2013-2014


CM Sitlani, J Dupuis, KM Rice, F Sun, AN Pitsillides, LA Cupples, and BM Psaty. Genome-Wide Gene-Environment Interactions on Quantitative Traits using Family Data. In press at European Journal of Human Genetics. PMID:26626313

PL Wander, CM Sitlani, SE Badon, DS Siscovick, MA Williams, DA Enquobahrie. Associations of Early and Late Gestational Weight Gain with Infant Birth Size.  PMID:26093689

CM Sitlani, KM Rice, T Lumley, B McKnight, LA Cupples, CL Avery, R Noordam, BHC Stricker, EA Whitsel, and BM Psaty. Generalized estimating equations for genome-wide association studies using longitudinal phenotype data. Statistics in Medicine, 34:118-130, 2015. PMID:25297442

Floyd JS, Sitlani CM, Wiggins, KL, Wallace E, Suchy-Dicey A, Carnethon MR, Siscovick DS, Sotoodehnia N, Heckbert SR, McKnight B, Rice K, Psaty BM. Variation in resting heart rate over four years and the risks of myocardial infarction and death among older adults. Heart, published online Sep 11, 2014. doi: 10.1136/heartjnl-2014-306046. PMID:25214500

GM Lawrence, S Shulman, Y Friedlander, CM Sitlani, A Burger, B Savitsky, E Granot-Hershkovitz, T Lumley, PY Kwok, S Hesselson, D Enquobahrie, PL Wander, O Manor, DS Siscovick, H Hochner. Associations of maternal pre-pregnancy and gestational body size with offspring longitudinal change in BMI. 2014-04-01. PMID:24124160

CM Sitlani, PJ Heagerty. Analyzing longitudinal data to characterize the accuracy of markers used to select treatment. 2014-03-13. PMID:24623550

RN Lemaitre, CO Johnson, S Hesselson, N Sotoodhenia, B McKnight, CM Sitlani, TD Rea, IB King, PY Kwok, A Mak, G Li, J Brody, E Larson, D Mozaffarian, BM Psaty, A Huertas-Vazquez, JC Tardif, CM Albert, LP Lyytikäinen, DE Arking, S Kääb, HV Huikuri, BP Krijthe, M Eijgelsheim, YA Wang, K Reinier, T Lehtimäki, SL Pulit, R Brugada, M Müller-Nurasyid, CH Newton-Cheh, PJ Karhunen, BH Stricker, P Goyette, JI Rotter, SS Chugh, A Chakravarti, X Jouven, DS Siscovick. Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest. 2014-03-01. PMID:24418166

CL Avery, CM Sitlani, DE Arking, DK Arnett, JC Bis, E Boerwinkle, BM Buckley, YD Ida Chen, AJ de Craen, M Eijgelsheim, D Enquobahrie, DS Evans, I Ford, ME Garcia, V Gudnason, TB Harris, SR Heckbert, H Hochner, A Hofman, WC Hsueh, A Isaacs, JW Jukema, P Knekt, JA Kors, BP Krijthe, K Kristiansson, M Laaksonen, Y Liu, X Li, PW Macfarlane, C Newton-Cheh, MS Nieminen, BA Oostra, GM Peloso, K Porthan, K Rice, FF Rivadeneira, JI Rotter, V Salomaa, N Sattar, DS Siscovick, PE Slagboom, AV Smith, N Sotoodehnia, DJ Stott, BH Stricker, T Stürmer, S Trompet, AG Uitterlinden, C van Duijn, RG Westendorp, JC Witteman, EA Whitsel, BM Psaty. Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. 2014-02-01. PMID:23459443

PL Wander, H Hochner, CM Sitlani, DA Enquobahrie, T Lumley, GM Lawrence, A Burger, B Savitsky, O Manor, V Meiner, S Hesselson, PY Kwok, DS Siscovick, Y Friedlander. Maternal Genetic Variation Accounts in Part for the Associations of Maternal Size during Pregnancy with Offspring Cardiometabolic Risk in Adulthood. PMID:24670385

BA Comstock, CM Sitlani, JG Jarvik, PJ Heagerty, JA Turner, DF Kallmes. Investigational vertebroplasty safety and efficacy trial (INVEST): patient-reported outcomes through 1 year. 2013-10-01. PMID:23696683

Thacker EL, McKnight B, Psaty BM, Longstreth WT Jr, Sitlani CM, Dublin S, Arnold AM, Fitzpatrick AL, Gottesman RF, Heckbert SR. Atrial fibrillation and cognitive decline: a longitudinal cohort study. Neurology. 2013 Jul 9;81(2):119-25. doi: 10.1212/WNL.0b013e31829a33d1.  PMID:23739229

BM Psaty, C Sitlani. The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium as a model of collaborative science. 2013-05-01. PMID:23549178

RN Lemaitre, C Sitlani, X Song, IB King, B McKnight, D Spiegelman, FM Sacks, L Djoussé, EB Rimm, DS Siscovick, D Mozaffarian. Circulating and dietary α-linolenic acid and incidence of congestive heart failure in older adults: the Cardiovascular Health Study. 2012-08-01. PMID:22743310

CM Sitlani, PJ Heagerty, EA Blood, TD Tosteson. Longitudinal structural mixed models for the analysis of surgical trials with noncompliance. 2012-07-20. PMID:22344923

KH Allison, PL Kandalaft, CM Sitlani, SM Dintzis, AM Gown. Routine pathologic parameters can predict Oncotype DX recurrence scores in subsets of ER positive patients: who does not always need testing? 2012-01-01. PMID:21369717

SM Dintzis, GY Stetsenko, CM Sitlani, AM Gronowski, ML Astion, TH Gallagher. Communicating pathology and laboratory errors: anatomic pathologists' and laboratory medical directors' attitudes and experiences. 2011-05-01. PMID:21502431

ML Weisfeldt, S Everson-Stewart, C Sitlani, T Rea, TP Aufderheide, DL Atkins, B Bigham, SC Brooks, C Foerster, R Gray, JP Ornato, J Powell, PJ Kudenchuk, LJ Morrison, Resuscitation Outcomes Consortium Investigators. Ventricular tachyarrhythmias after cardiac arrest in public versus at home. 2011-01-27. PMID:21268723

CM Sitlani, B McKnight. Relative efficiency of trend tests with misspecified genetic models in stratified analyses of case-control or cohort data. 2011-01-01. PMID:21811075

ML Weisfeldt, CM Sitlani, JP Ornato, T Rea, TP Aufderheide, D Davis, J Dreyer, EP Hess, J Jui, J Maloney, G Sopko, J Powell, G Nichol, LJ Morrison, ROC Investigators. Survival after application of automatic external defibrillators before arrival of the emergency medical system: evaluation in the resuscitation outcomes consortium population of 21 million. 2010-04-20. PMID:20394876

J Sugarman, C Sitlani, D Andrusiek, T Aufderheide, EM Bulger, DP Davis, DB Hoyt, A Idris, JD Kerby, J Powell, T Schmidt, AS Slutsky, G Sopko, S Stephens, C Williams, G Nichol, Resuscitation Outcomes Consortium Investigators. Is the enrollment of racial and ethnic minorities in research in the emergency setting equitable? 2009-06-01. PMID:19395144