Cardiovascular Health Research Unit

Rozenn Lemaitre, PhD, MPH

Research Associate Professor, Medicine
Adjunct Research Associate Professor, Epidemiology
Affiliate Investigator, Nutrition Obesity Research Center

rozenlu.washington.edu

Education

PhD, Biochemistry, Montana State University, Bozeman, MT, 1982
MPH, Epidemiology, University of Washington, Seattle, WA, 1994


Interests

Cardiovascular epidemiology
Sudden cardiac death
Diabetes
Lipidomics
Genetics
Nutrition


Honors

CHARGE Consortium. Working Group Leadership Award, 2014.


Publications

RN Lemaitre, IB King, EK Kabagambe, JH Wu, B McKnight, A Manichaikul, W Guan, Q Sun, DI Chasman, M Foy, L Wang, J Zhu, DS Siscovick, MY Tsai, DK Arnett, BM Psaty, L Djousse, YD Chen, W Tang, LC Weng, H Wu, MK Jensen, AY Chu, DR Jacobs, SS Rich, D Mozaffarian, L Steffen, EB Rimm, FB Hu, PM Ridker, M Fornage, Y Friedlander. Genetic loci associated with circulating levels of very long-chain saturated fatty acids. 2015-01-01. PMID:25378659

RN Lemaitre, IB King, K Rice, B McKnight, N Sotoodehnia, TD Rea, CO Johnson, TE Raghunathan, LA Cobb, D Mozaffarian, DS Siscovick. Erythrocyte very long-chain saturated fatty acids associated with lower risk of incident sudden cardiac arrest. 2014-10-01. PMID:25107579

Fretts AM, Mozaffarian D, Siscovick DS, Djousse L, Heckbert SR, King IB, McKnight B, Sitlani C, Sacks FM, Song X, Sotoodehnia N, Spiegelman D, Wallace ER, Lemaitre RN. Plasma phospholipid saturated fatty acids and incident atrial fibrillation: the Cardiovascular Health Study.  J Am Heart Assoc. 2014 Jun 26;3(3).  PMID:24970268

RN Lemaitre, CO Johnson, S Hesselson, N Sotoodhenia, B McKnight, CM Sitlani, TD Rea, IB King, PY Kwok, A Mak, G Li, J Brody, E Larson, D Mozaffarian, BM Psaty, A Huertas-Vazquez, JC Tardif, CM Albert, LP Lyytikäinen, DE Arking, S Kääb, HV Huikuri, BP Krijthe, M Eijgelsheim, YA Wang, K Reinier, T Lehtimäki, SL Pulit, R Brugada, M Müller-Nurasyid, CH Newton-Cheh, PJ Karhunen, BH Stricker, P Goyette, JI Rotter, SS Chugh, A Chakravarti, X Jouven, DS Siscovick. Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest. 2014-03-01. PMID:24418166

Long-chain monounsaturated Fatty acids and incidence of congestive heart failure in 2 prospective cohorts. Imamura F, Lemaitre RN, King IB, Song X, Steffen LM, Folsom AR, Siscovick DS, Mozaffarian D. Circulation. 2013 Apr 9;127(14):1512-21, 1521e1-18. doi: 10.1161/CIRCULATIONAHA.112.001197. Epub 2013 Mar 13. PMID:23487436

Wu, J.H.Y., Lemaitre,R.N., Manichaikul, A., Guan, W., Tanaka, T., Foy, M., Kabagambe, E.K., Djousse, L., Siscovick, D., Fretts, A.M.,  Johnson, C., King, I.B., Psaty, B.M., McKnight, B., Rich, S.S., Chen, Y.I., Nettleton, J.A., Tang, W.,  Bandinelli, S., Jacobs, D.R., Browning, B.L., Laurie, C.C., Gu, X., Tsai, M.Y., Steffen, L.M., Ferrucci, L., Fornage, M., Mozaffarian, D. Genome-Wide Association Study Identifies Novel Loci Associated With Concentrations of Four Plasma Phospholipid Fatty Acids in the De Novo Lipogenesis Pathway: Results from the CHARGE Consortium. Circulation: Cardiovascular Genetics. 2013 Apr; 6(2): 171-83.  PMID:23362303

D Mozaffarian, RN Lemaitre, IB King, X Song, H Huang, FM Sacks, EB Rimm, M Wang, DS Siscovick. Plasma phospholipid long-chain ω-3 fatty acids and total and cause-specific mortality in older adults: a cohort study.  Ann Intern Med. 2013 Apr 2;158(7):515-25. doi: 10.7326/0003-4819-158-7-201304020-00003. PMID:23546563

D Mozaffarian, MC de Oliveira Otto, RN Lemaitre, AM Fretts, G Hotamisligil, MY Tsai, DS Siscovick, JA Nettleton. trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA). 2013-04-01. PMID:23407305

Common variation in fatty acid genes and resuscitation from sudden cardiac arrest. Johnson CO, Lemaitre RN, Fahrenbruch CE, Hesselson S, Sotoodehnia N, McKnight B, Rice KM, Kwok PY, Siscovick DS, Rea TD. Circ Cardiovasc Genet. 2012 Aug 1;5(4):422-9. doi: 10.1161/CIRCGENETICS.111.961912. Epub 2012 Jun 1. Erratum in: Circ Cardiovasc Genet. 2013 Feb;6(1):e1. PMID:22661490

Fretts AM, Mozaffarian D, Siscovick DS, Heckbert SR, McKnight B, King IB, Rimm EB, Psaty BM, Sacks FM, Song X, Spiegelman D, Lemaitre RN.  J Am Heart Assoc. 2013 Jan 31;2(1) PMID:23525429

Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. Nettleton JA, Hivert MF, Lemaitre RN, et. al. Am J Epidemiol. 2013 Jan 15;177(2):103-15. doi: 10.1093/aje/kws297. Epub 2012 Dec 19. Review. PMID:23255780

RN Lemaitre, C Sitlani, X Song, IB King, B McKnight, D Spiegelman, FM Sacks, L Djoussé, EB Rimm, DS Siscovick, D Mozaffarian. Circulating and dietary α-linolenic acid and incidence of congestive heart failure in older adults: the Cardiovascular Health Study. 2012-08-01. PMID:22743310

Fatty acids in the de novo lipogenesis pathway and risk of coronary heart disease: the Cardiovascular Health Study. Wu JH, Lemaitre RN, Imamura F, King IB, Song X, Spiegelman D, Siscovick DS, Mozaffarian D. Am J Clin Nutr. 2011 Aug;94(2):431-8. PMID:21697077

Trans-palmitoleic acid, metabolic risk factors, and new-onset diabetes in U.S. adults: a cohort study. Mozaffarian D, Cao H, King IB, Lemaitre RN, Song X, Siscovick DS, Hotamisligil GS. Ann Intern Med. 2010 Dec 21;153(12):790-9. PMID:21173413

Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN et. al. Diabetes Care. 2010 Dec;33(12):2684-91. PMID:20693352